Determination of Complex Isotopomer Patterns in Isotopically Labeled Compounds by Mass Spectrometry

Dynamics of silicate species in solution studied by mass spectrometry with isotopically labeled compounds.

Quantifying peptides in isotopically labeled protease digests by ion mobility/time-of-flight mass spectrometry.

Ion mobility/time-of-flight techniques have been used to analyze mixtures of isotopically labeled peptides. The isotopic labels were generated by treatment of peptides with N-acetoxysuccinimide (or the deuterated analogue), which results in acetylation (or deuterioacetylation) of the primary amines (i.e., the N-terminus and lysine residues). The relative concentrations of a peptide in each samp...

Differentiation of isotopically labeled nucleotides using fast atom bombardment tandem mass spectrometry.

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Determination of Mebudipine in Human Plasma by Liquid Chromatography–tandem Mass Spectrometry

In previous studies, mebudipine, a dihydropyridine calcium channel blocker, showed a considerable potential to be used in cardiovascular diseases. The aim of the current study was to develop a valid method using reversed-phase high performance liquid chromatography coupled with electrospray ionization mass spectrometry to assay mebudipine in the human plasma. Separation was achieved on a Zorbax...

Perchloroethylene Analysis by Chemical Oxidation and Determination of Intermediate Products by Gas Chromatography, Mass Spectrometry

Abstract Background and Objective: Perchloroethylene (PCE) is a chlorinated hydrocarbon used as a solvent in many industrial processes. In contaminated water and soil a great deal of PCE is found. This study aimed to determine the rate of decomposition of PCE occurred after advanced oxidation. Material and Methods: In this descriptive-analytic study conducted (2011) in public health faculty...